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doi:10.3899/jrheum.120989

4 Studies in animals have led to concerns about the risk of acute pancreatitis and medullary thyroid carcinoma (MTC)

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Contrary, NP4 showed a cytotoxic effect in the very low micromolar range (143B: IC 50 = 6.6 M, K7M2: IC 50 = 2.1 M) (drug-response curves: Fig